It's been a long term rant of mine that local businesses in Buffalo seldom branch out, leaving out-of-towners to capitalize on the city's assets. It seems like some mom-and-pop restaurant in Columbus will become a national chain a couple of years after first opening, while some immensely popular restaurant in Buffalo might open one or two more local branches, tops, with maybe one oddball location in Sarasota or whereever -- if they do branch out at all. Buffalo's entrepreneurial culture is big about staying small and local.
When Buffalo style pizza finally gets discovered, it'll probably be some new chain outside of the region that takes it national. Something with a name like "Cheektowaga Cup N' Char", probably based out of an office park in Dublin or New Albany, Ohio.